Nah, I'd mark that point a few episodes back. When you have two men of science opt for brawn over brains so that Fox executives can call the show an action adventure show. That and the whole L.A. move was bad, they cut off all the old side characters because it cost too much to fly them down from Canada. Plus she-Quinn wasn't "sexy" enough for her planned returns. o.O
Normally, I'd put advanced evil aliens (kromags here) or secret governmental agencies chasing them down as a turning point. But changing characters 180 degrees and moving to a more expensive location which cuts into the budget for FXs are just as bad here.
I could buy into dragons, wizards, dream assassins, and all the other hokey pokey if they would have kept the character foundation of the first two seasons.